THE BASIC PRINCIPLES OF METHYLATED DNA

The procedure of HPLC-UV (substantial functionality liquid chromatography-ultraviolet), formulated by Kuo and colleagues in 1980 [seventeen], continues to be regarded as the current “gold standard” assay for quantifying the amount of deoxycytidine (dC) and methylated cytosines (five mC) existing within a hydrolysed DNA sample. nonetheless, the